On May 28, 1987, the Chicago Bears' running back Walter Payton became the first player in NFL history to score 100 career rushing touchdowns.

On May 28, 1979, the first-ever 'test-tube baby,' Louise Brown, was conceived through in vitro fertilization, changing the landscape of reproductive science.

On May 28, 1969, the first-ever human-crewed spacecraft, Apollo 10, was launched, serving as a rehearsal for the first moon landing.