On June 5, 2017, the United States withdrew from the Paris Agreement on climate change, a decision announced by President Donald Trump that drew widespread international criticism.

On June 5, 1981, the Centers for Disease Control and Prevention (CDC) published a report detailing cases of a rare pneumonia in five young gay men, marking one of the first public mentions of what would later be identified as AIDS.

On June 5, 1968, U.S. Senator Robert F. Kennedy was assassinated in Los Angeles shortly after delivering a victory speech upon winning the California primary.